Pognan, F.: search on Z-Library

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1

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

John O'Brien, Ian Wilson, Terry Orton, François Pognan

Journal:

Year:

2000

Language:

english

File:

PDF, 651 KB

english, 2000

2

Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation

Manevski, N., Swart, P., Balavenkatraman, K. K., Bertschi, B., Camenisch, G., Kretz, O., Schiller, H., Walles, M., Ling, B., Wettstein, R., Schaefer, D. J., Itin, P., Ashton-Chess, J., Pognan, F., Wol

Journal:

Drug Metabolism and Disposition

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

3

An Integrated Metabonomic Investigation of Acetaminophen Toxicity in the Mouse Using NMR Spectroscopy

Coen, Muireann, Lenz, Eva M., Nicholson, Jeremy K., Wilson, Ian D., Pognan, Francois, Lindon, John C.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

4

Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin

Brecht, Karin, Riebel, Virginie, Couttet, Philippe, Paech, Franziska, Wolf, Armin, Chibout, Salah-Dine, Pognan, Francois, Krähenbühl, Stephan, Uteng, Marianne

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 2.33 MB

english, 2017

5

Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human

Journal:

Toxicology Letters

Year:

2018

Language:

english

File:

PDF, 51 KB

english, 2018

6

Imatinib does not induce cardiotoxicity at clinically relevant concentrations in preclinical studies

Armin Wolf, Philippe Couttet, Min Dong, Olivier Grenet, Marcia Heron, Ursula Junker, Ulrich Laengle, David Ledieu, Estelle Marrer, Anja Nussher, Elke Persohn, Francois Pognan, Gilles-Jacques Rivière,

Journal:

Leukemia Research

Year:

2010

Language:

english

File:

PDF, 452 KB

english, 2010

7

Pharmacodynamic profiling of EGFR inhibitors in human keratinocytes

Balavenkatraman, K.K., Vicart, A., Couttet, P., Ledieu, D., Hopfer, U., Rathfelder, N., Bertschi, B., Greutmann, B., Marcellin, M., Chibout, S.D., Lambert, A., Moggs, J., Pognan, F., Wolf, A.

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 96 KB

english, 2013

8

Preclinical evaluation of potential nilotinib cardiotoxicity

Armin Wolf, Philippe Couttet, Min Dong, Olivier Grenet, Marcia Heron, Ursula Junker, David Ledieu, Andreas Mahl, Estelle Marrer, Elke Persohn, Francois Pognan, Wei Zhou, Jeffrey Tsao, Danielle Roman

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

9

Genome-wide analysis of DNA methylation profiles in a preclinical animal model of non-genotoxic carcinogenesis

Jonathan Moggs, Soon Siong Teo, Arne Mueller, Laurent Morawiec, Tim Roloff, David Heard, Frank Staedtler, Dirk Schubeler, Fabian Mohn, Jay Goodman, Jennifer Phillips, Natasa Zamurovic, Francois Pognan

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

10

Development of a Novel LC-MS/MS Method to Quantify F2-Isoprostanes in Biological Samples

Min Dong, Falk Rohrbach, Marianne Schwald, Odile Weber, Virginie Riebel, Francois Pognan, Armin Wolf

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 184 KB

english, 2010

11

In silico prediction of in vivo toxicity - the first steps of the e-Tox consortium

T. Steger-Hartmann, F. Pognan, F. Sanz, C. Diaz, A. Sutter, M. Pastor

Journal:

Toxicology Letters

Year:

2010

Language:

english

File:

PDF, 89 KB

english, 2010

12

Genomics, proteomics and metabonomics in toxicology: hopefully not ‘fashionomics’

Pognan, Francois

Journal:

Pharmacogenomics

Year:

2004

Language:

english

File:

PDF, 196 KB

english, 2004

13

Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human

Pognan, Francois, Mahl, J. Andreas, Papoutsi, Maria, Ledieu, David, Raccuglia, Marc, Theil, Diethilde, Voytek, Sarah B., Devine, Patrick J., Kubek-Luck, Katie, Claudio, Natalie, Cordier, Andre, Heier,

Journal:

Archives of Toxicology

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

14

Establishment of a rat Sertoli cell line that displays the morphological and some of the functional characteristics of the native cell

F. Pognan, M.-T. Masson, F. Lagelle, C. Charuel

Journal:

Cell Biology and Toxicology

Year:

1997

Language:

english

File:

PDF, 633 KB

english, 1997

15

Books received

Riebel, Virginie, Brecht, K., Bonifacio, A., Marcellin, M., Couttet, P., Chibout, S.D., Pognan, F., Wolf, A., Uteng, M.

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1972

Language:

english

File:

PDF, 38 KB

english, 1972

16

Investigative safety science as a competitive advantage for Pharma

Moggs, Jonathan, Moulin, Pierre, Pognan, Francois, Brees, Dominique, Leonard, Michele, Busch, Steve, Cordier, Andre, Heard, David J, Kammüller, Michael, Merz, Michael, Bouchard, Page, Chibout, Salah-D

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2012

Language:

english

File:

PDF, 313 KB

english, 2012

17

CSF-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes

Pognan, Francois, Couttet, Philippe, Demin, Ivan, Jaitner, Birgit, Pang, Yinuo, Roubenoff, Ronenn, Sutter, Esther, Timsit, Yoav, Valentin, Marie Anne, Vogel, Beate, Woerly, Gaetane, Wolf, Armin, Schra

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

File:

PDF, 2.13 MB

2019

18

Does cruciform DNA provide a recognition signal for DNA-topoisomerase II?

F. Pognan, C. Paoletti

Journal:

Year:

1992

Language:

english

File:

PDF, 437 KB

english, 1992

19

Bile acids profiling of rat plasma after treatment with Cyclosporin A

Schadt, Heiko, Stiehl, Daniel, Schwald, Marianne, Vieira, Catia Vicente, Dietz, Audrey, Penno, Carlos, Chibout, Salah-Dine, Moulin, Pierre, Pognan, Francois, Wolf, Armin

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 73 KB

english, 2014

20

Determination of liver specific toxicities in rat hepatocytes by high content imaging during 2-week multiple treatment

Germano, Davide, Uteng, Marianne, Pognan, Francois, Chibout, Salah-Dine, Wolf, Armin

Journal:

Toxicology in Vitro

Year:

2014

Language:

english

File:

PDF, 5.28 MB

english, 2014

21

OntoBrowser: a collaborative tool for curation of ontologies by subject matter experts

Ravagli, Carlo, Pognan, Francois, Marc, Philippe

Journal:

Year:

2016

Language:

english

File:

PDF, 132 KB

english, 2016

22

Determination of liver specific toxicities in rat hepatocytes by High Content Imaging during 2-week multiple treatment

Germano, Davide, Uteng, Marianne, Couttet, Philippe, Grenet, Olivier, Chibout, Salah-Dine, Pognan, Francois, Wolf, Armin

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 96 KB

english, 2013

23

Aldehyde Oxidase Activity in Fresh Human Skin

Manevski, N., Balavenkatraman, K. K., Bertschi, B., Swart, P., Walles, M., Camenisch, G., Schiller, H., Kretz, O., Ling, B., Wettstein, R., Schaefer, D. J., Pognan, F., Wolf, A., Litherland, K.

Journal:

Drug Metabolism and Disposition

Year:

2014

Language:

english

File:

PDF, 858 KB

english, 2014

24

Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

Atienzar, Franck A., Blomme, Eric A., Chen, Minjun, Hewitt, Philip, Kenna, J. Gerry, Labbe, Gilles, Moulin, Frederic, Pognan, Francois, Roth, Adrian B., Suter-Dick, Laura, Ukairo, Okechukwu, Weaver, R

Journal:

BioMed Research International

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

25

The Genetics of Pyloric Stenosis

Lamy, Maurice, Pognan, Mme Cl., Maroteau, P.

Journal:

Proceedings of the Royal Society of Medicine

Year:

1953

File:

PDF, 291 KB

1953

26

Synthesis and Structure-Activity Relationship of Methyl-Substituted Indolo[2,3-b]quinolines: Novel Cytotoxic, DNA Topoisomerase II Inhibitors

Peczynska-Czoch, Wanda, Pognan, Francois, Kaczmarek, Lukasz, Boratynski, Janusz

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.45 MB

english, 1994

27

Comparative renal safety assessment of the hepatitis B drugs, adefovir, tenofovir, telbivudine and entecavir in rats

Uteng, Marianne, Mahl, Andreas, Beckmann, Nicolau, Piaia, Alessandro, Ledieu, David, Dubost, Valerie, Tritto, Elaine, Wolf, Armin, Moulin, Pierre, Li, Li, Chibout, Salah-Dine, Pognan, Francois

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 2.40 MB

english, 2016

28

Legacy data sharing to improve drug safety assessment: the eTOX project

Sanz, Ferran, Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Cases, Montserrat, Pastor, Manuel, Marc, Philippe, Wichard, Joerg, Briggs, Katharine, Watson, David K., Kleinöder, Thomas, Yang,

Journal:

Nature Reviews Drug Discovery

Year:

2017

Language:

english

File:

PDF, 118 KB

english, 2017

29

A carboline derivative as a novel mammalian DNA topoisomerase II targeting agent

François Pognan, Jean-Marie Saucier, Claude Paoletti, Lukasz Kaczmarek, Pawel Nantka-Namirski, Marian Mordarski, Wanda Peczynska-Czoch

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 990 KB

english, 1992

30

Learning from approved kinase inhibitors to better inform on the safety risks of specific kinases

Vicart, Axel, Kinyamu-Akunda, Jacqueline, Whitebread, Steven, Dumotier, Berengere, Urban, Laszlo, Kluwe, William, Moggs, Jonathan, Pognan, François, Chibout, Salah-Dine

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 54 KB

english, 2017

31

CSF-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes

Pognan, Francois, Couttet, Philippe, Demin, Ivan, Jaitner, Birgit, Pang, Yinuo, Roubenoff, Ronenn, Sutter, Esther, Timsit, Yoav, Valentin, Marie Anne, Vogel, Beate, Woerly, Gaetane, Wolf, Armin, Schra

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

Language:

english

File:

PDF, 2.13 MB

english, 2019

32

MYOPATHIE ET DALTONISME : ANALYSE D'UN PEDIGREE

PAR JEAN FRÉZAL, J. DE GROUCHY, MAURICE LAMY, MME C. POGNAN

Journal:

Annals of Human Genetics

Year:

1957

Language:

french

File:

PDF, 379 KB

french, 1957

33

Bile acids in drug induced liver injury: Key players and surrogate markers

Schadt, Heiko S., Wolf, Armin, Pognan, Francois, Chibout, Salah-Dine, Merz, Michael, Kullak-Ublick, Gerd A.

Journal:

Clinics and Research in Hepatology and Gastroenterology

Year:

2016

Language:

english

File:

PDF, 1.76 MB

english, 2016

34

The IMI eTOX initiative – Data mining, read-across and predictive models for target evaluation and early drug candidate assessment

Steger-Hartmann, Thomas, Pognan, Francois, Sanz, Ferran

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 84 KB

english, 2017

35

The Use of Rat Lens Explant Cultures to Study the Mechanism of Drug-Induced Cataractogenesis

Sampath, S., McLean, L. A., Buono, C., Moulin, P., Wolf, A., Chibout, S.-D., Pognan, F., Busch, S., Shangari, N., Cruz, E., Gurnani, M., Patel, P., Reising, A.

Journal:

Toxicological Sciences

Year:

2012

Language:

english

File:

PDF, 754 KB

english, 2012

36

A new extraction procedure of autonomous DNA from eucaryotic cells, where DNA could be bound to proteins

Pognan, F., Paoletti, C.

Journal:

Nucleic Acids Research

Year:

1990

Language:

english

File:

PDF, 1.46 MB

english, 1990

37

ATNT-12PHASE I, TWO-STAGE, OPEN-LABEL, DOSE-ESCALATION STUDY OF BUPARLISIB (BKM120) IN COMBINATION WITH ADJUVANT TEMOZOLOMIDE (TMZ) AND WITH CONCOMITANT RADIATION THERAPY (RT) AND TMZ IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM)

Rodon, Jordi, Rosenthal, Mark, Mason, Warren, Segura, Pedro Perez, Beck, Joseph T., Hirte, Holger, DeGroot, John F., Trandafir, Lucia, Pognan, Nathalie, Yang, Lin, Kanwal, Charu, Wen, Patrick Y.

Journal:

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

38

Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology

Robert Tonge, Joanne Shaw, Brian Middleton, Rachel Rowlinson, Steve Rayner, Janice Young, Francois Pognan, Edward Hawkins, Ian Currie, Matthew Davison

Journal:

Year:

2001

Language:

english

File:

PDF, 4.37 MB

english, 2001

39

Arctigenin's mode of toxicity in oxidative metabolizing cell lines

Riebel, Virginie, Brecht, K., Bonifacio, A., Marcellin, M., Couttet, P., Chibout, S.D., Pognan, F., Wolf, A., Uteng, M.

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 73 KB

english, 2013

40

α-Anomeric DNA: β-RNA hybrids as new synthetic inhibitors of Escherichia coli RNase H, Drosophila embryo RNase H and M-MLV reverse transcriptase

Bloch, Evelyne, Lavignon, Marc, Bertrand, Jean-Rémi, Pognan, François, Morvan, François, Malvy, Claude, Rayner, Bernard, Imbach, Jean-Louis, Paoletti, Claude

Journal:

Year:

1988

Language:

english

File:

PDF, 1.23 MB

english, 1988

41

1106 TELBIVUDINE DOES NOT CAUSE MITOCHONDRIAL TOXICITY IN HUMAN SKELETAL MUSCLE CELLS AND NEURONAL CELLS

Dong, M., Persohn, E., Grenet, O., Chibout, S.-D., Pognan, F., Wolf, A., Weaver, M., Li, L.

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

42

Investigation of Correlation Among Safety Biomarkers in Serum, Histopathological Examination, and Toxicogenomics

Wang, T., Papoutsi, M., Wiesmann, M., DeCristofaro, M., Keselica, M. C., Skuba, E., Spaet, R., Markovits, J., Wolf, A., Moulin, P., Pognan, F., Vancutsem, P., Petryk, L., Sutton, J., Chibout, S.-D., K

Journal:

International Journal of Toxicology

Year:

2011

Language:

english

File:

PDF, 227 KB

english, 2011

43

Mechanistic Investigation of N,N-Diethyl-4-(phenyl-piperidin-4-ylidenemethyl)-benzamide-Induced Insulin Depletion in the Rat and RINm5F Cells

Otieno, M. A., Bavuso, N., Milano, J., Foster-Brown, L., Bui, K.-H., Li, Y., Hudzik, T., Wescott, D., Louden, C., Dyroff, M., Pognan, F.

Journal:

Toxicological Sciences

Year:

2008

Language:

english

File:

PDF, 880 KB

english, 2008

44

Preclinical ontologies – A key feature for toxicity data exchange and mining

Drew, Philip, Pognan, Francois, Marc, Philippe, Ravagli, Carlo

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 84 KB

english, 2017

45

Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation

Schumann, J., Grevot, A., Ledieu, D., Wolf, A., Schubart, A., Piaia, A., Sutter, E., Cote, S., Beerli, C., Pognan, F., Billich, A., Moulin, P., Walker, U. J.

Journal:

Toxicologic Pathology

Year:

2015

Language:

english

File:

PDF, 1.97 MB

english, 2015

46

In silico prediction of in vivo toxicities (eTox)—The Innovative Medicines Initiative Approach

Thomas Steger-Hartmann, Francois Pognan, Ferran Sanz, Carlos Acedo Diaz

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

47

Ensuring confidence in predictions: A scheme to assess the scientific validity of in silico models

Hewitt, Mark, Ellison, Claire M., Cronin, Mark T.D., Pastor, Manuel, Steger-Hartmann, Thomas, Munoz-Muriendas, Jordi, Pognan, Francois, Madden, Judith C.

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 1.60 MB

english, 2015

48

Searching for super-Eddington quasars using a photon trapping accretion disc model

Pognan, Quentin, Trakhtenbrot, Benny, Sbarrato, Tullia, Schawinski, Kevin, Bertemes, Caroline

Journal:

Monthly Notices of the Royal Astronomical Society

Year:

2020

File:

PDF, 2.49 MB

2020

49

Validation of anin vitroscreen for phospholipidosis using a high-content biology platform

J. K. Morelli, M. Buehrle, F. Pognan, L. R. Barone, W. Fieles, P. J. Ciaccio

Journal:

Cell Biology and Toxicology

Year:

2006

Language:

english

File:

PDF, 593 KB

english, 2006

50

A novel method for quantification of canalicular transporter inhibition in primary rat hepatocyte sandwich cultures

Jane Hopwood, Claire Summers, François Pognan, Gillian Barrett, Kevin Jones, Romuald Laine, Gerry Kenna

Journal:

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

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